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NDB ID: PD0102    PDB ID: 1DH3 


Title:

CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING

Molecular Description:

TRANSCRIPTION FACTOR CREB/DNA COMPLEX

Deposited:

1999-11-27

Released:

2000-11-27

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Schumacher, M.A., Goodman, R.H., Brennan, R.G.
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding 
J.Biol.Chem., 275, pp. 35242 - 35247, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 110.61   b = 49.32   c = 79.25 (Ångstroms)

α = 90.0   β = 122.18   γ = 90.0 (degrees)

Refinement:

The structure was refined using the TNT program. The R value is 0.218 for 7316 reflections in the resolution range 10.0 to 3.0 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  1.0 sigma(I)