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NDB ID: PD0115    PDB ID: 1DSZ 


Title:

STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1

Molecular Description:

RETINOIC ACID RECEPTOR RXR ALPHA AND RAR ALPHA/DNA COMPLEX

Deposited:

2000-01-10

Released:

2000-07-10

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Rastinejad, F., Wagner, T., Zhao, Q., Khorasanizadeh, S.
Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1. 
EMBO J., 19, pp. 1045 - 1054, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 80.66   b = 33.9   c = 101.86 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.201 for 28332 reflections in the resolution range 20.0 to 1.7 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  1.0 sigma(I)