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NDB ID: PD0134    PDB ID: 1QAJ 


Title:

CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN

Molecular Description:

REVERSE TRANSCRIPTASE (E.C.2.7.7.49)/DNA COMPLEX

Deposited:

1999-03-18

Released:

2000-04-02

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Najmudin, S., Cote, M.L., Sun, D., Yohannan, S., Montano, S.P., Gu, J., Georgiadis, M.M.
Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain. 
J.Mol.Biol., 296, pp. 613 - 632, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 65.868   b = 63.587   c = 73.398 (Ångstroms)

α = 90.0   β = 102.91   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2 for 26120 reflections in the resolution range 20.0 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)