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NDB ID: PD0195    PDB ID: 1HU0 


Title:

CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX

Molecular Description:

8-OXOGUANINE DNA GLYCOSYLASE 1 (E.C. 3.2.2.-)/DNA COMPLEX

Deposited:

2001-01-03

Released:

2003-02-25

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Fromme, J.C., Bruner, S.D., Yang, W., Karplus, M., Verdine, G.L.
Product-Assisted Catalysis in base-excision DNA Repair 
Nat.Struct.Biol., 10, pp. 204 - 211, 2003.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 91.988   b = 91.988   c = 211.615 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.21 for 18696 reflections in the resolution range 42.14 to 2.35 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  2.0 sigma(I)