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NDB ID: PD0243    PDB ID: 1MHD 


Title:

CRYSTAL STRUCTURE OF A SMAD MH1 DOMAIN BOUND TO DNA

Molecular Description:

SMAD3/DNA Complex

Deposited:

1998-08-18

Released:

1999-08-18

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shi, Y., Wang, Y.F., Jayaraman, L., Yang, H., Massague, J., Pavletich, N.P.
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. 
Cell(Cambridge,Mass.), 94, pp. 585 - 594, 1998.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 45.6   b = 60.4   c = 71.6 (Ångstroms)

α = 90.0   β = 102.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.212 for 8490 reflections in the resolution range 8.0 to 2.8 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)