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NDB ID: PD0307    PDB ID: 1LE5 


Title:

CRYSTAL STRUCTURE OF A NF-KB HETERODIMER BOUND TO AN IFNB-KB

Molecular Description:

Nuclear factor NF-kappa-B p65 subunit/Nuclear factor NF-kappa-B p50 subunit/DNA Complex

Deposited:

2002-04-09

Released:

2003-04-15

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Berkowitz, B., Huang, D.B., Chen-Park, F.E., Sigler, P.B., Ghosh, G.
The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site 
J.Biol.Chem., 277, pp. 24694 - 24700, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 137.525   b = 138.015   c = 89.32 (Ångstroms)

α = 90.0   β = 97.25   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 37688 reflections in the resolution range 20.0 to 2.75 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)