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NDB ID: PD0310    PDB ID: 1LEI 


Title:

THE KB DNA SEQUENCE FROM THE HLV-LTR FUNCTIONS AS AN ALLOSTERIC REGULATOR OF HIV TRANSCRIPTION

Molecular Description:

NUCLEAR FACTOR NF-KAPPA-B P65 SUBUNIT/NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT/DNA Complex

Deposited:

2002-04-09

Released:

2003-04-15

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Chen-Park, F.E., Huang, D.B., Noro, B., Thanos, D., Ghosh, G.
The kB DNA sequence from the HIV Long Terminal Repeat functions as an allosteric regulator of HIV transcription 
J.Biol.Chem., 277, pp. 24701 - 24708, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 2

Cell Constants:

a = 137.131   b = 179.697   c = 97.068 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 29985 reflections in the resolution range 20.0 to 2.7 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)