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NDB ID: PD0332    PDB ID: 1M3Q 


Title:

CRYSTAL STRUCTURE OF HOGG1 D268E MUTANT WITH BASE-EXCISED DNA AND 8-AMINOGUANINE

Molecular Description:

8-oxoguanine DNA glycosylase (E.C.3.2.2.-)/DNA Complex

Deposited:

2002-06-28

Released:

2004-02-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chung, S.J., Verdine, G.L.
Structures of End Products Resulting from Lesion Processing by a DNA Glycosylase/Lyase 
Chem.Biol., 11, pp. 1643 - 1649, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 92.415   b = 92.415   c = 211.425 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 37734 reflections in the resolution range 37.43 to 1.9 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)