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NDB ID: PD0356    PDB ID: 1N3C 


Title:

STRUCTURAL AND BIOCHEMICAL EXPLORATION OF A CRITICAL AMINO ACID IN HUMAN 8-OXOGUANINE GLYCOSYLASE

Molecular Description:

Deposited:

2002-10-25

Released:

2003-03-04

Structural Keywords:

B DOUBLE HELIX, FLIPPED OUT BASE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Norman, D.P., Chung, S.J., Verdine, G.L.
Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase 
Biochemistry, 42, pp. 1564 - 1572, 2003.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 92.255   b = 92.255   c = 210.6 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.225 for 14167 reflections in the resolution range 29.03 to 2.7 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)