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NDB ID: PD0364    PDB ID: 1N6Q 


Title:

HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO PRE-TRANSLOCATION AZTMP-TERMINATED DNA (COMPLEX N)

Molecular Description:

Deposited:

2002-11-11

Released:

2003-01-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Sarafianos, S.G., Clark Jr., A.D., Das, K., Tuske, S., Birktoft, J.J., Ilankumaran, I., Ramesha, A.R., Sayer, J.M., Jerina, D.M., Boyer, P.L., Hughes, S.H., Arnold, E.
Structures of HIV-1 Reverse Transcriptase with Pre- and Post-translocation AZTMP-terminated DNA 
Embo J., 21, pp. 6614 - 6624, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 1 2

Cell Constants:

a = 166.35   b = 166.35   c = 220.96 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 59280 reflections in the resolution range 20.0 to 3.0 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)