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NDB ID: PD0506    PDB ID: 1RZ9 


Title:

CRYSTAL STRUCTURE OF AAV REP COMPLEXED WITH THE REP-BINDING SEQUENCE

Molecular Description:

Rep PROTEIN/DNA Complex

Deposited:

2003-12-24

Released:

2004-02-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hickman, A.B., Ronning, D.R., Perez, Z.N., Kotin, R.M., Dyda, F.
The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces. 
Mol.Cell, 13, pp. 403 - 414, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 78.671   b = 131.706   c = 82.164 (Ångstroms)

α = 90.0   β = 112.68   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.286 for 23530 reflections in the resolution range 19.88 to 3.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)