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NDB ID: PD0510    PDB ID: 1S0O 


Title:

SNAPSHOTS OF REPLICATION THROUGH AN ABASIC LESION: STRUCTURAL BASIS FOR BASE SUBSTITUTION AND FRAMESHIFT

Molecular Description:

DNA polymerase IV(E.C.2.7.7.7)/DNA Complex

Deposited:

2003-12-31

Released:

2004-03-30

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ling, H., Boudsocq, F., Woodgate, R., Yang, W.
Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts. 
Mol.Cell, 13, pp. 751 - 762, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 98.301   b = 103.046   c = 105.912 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.229 for 61046 reflections in the resolution range 30.0 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)