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NDB ID: PD0540    PDB ID: 1T2K 


Title:

STRUCTURE OF THE DNA BINDING DOMAINS OF IRF3, ATF-2 AND JUN BOUND TO DNA

Molecular Description:

Deposited:

2004-04-21

Released:

2004-11-16

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Panne, D., Maniatis, T., Harrison, S.C.
Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. 
Embo J., 23, pp. 4384 - 4393, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 186.38   b = 65.21   c = 83.85 (Ångstroms)

α = 90.0   β = 93.44   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.257 for 20140 reflections in the resolution range 29.98 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)