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NDB ID: PD0582    PDB ID: 1U49 


Title:

ADENINE-8OXOGUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE

Molecular Description:

DNA polymerase I (E.C.2.7.7.7)/DNA Complex

Deposited:

2004-07-23

Released:

2004-09-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hsu, G.W., Ober, M., Carell, T., Beese, L.S.
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. 
Nature, 431, pp. 217 - 221, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 87.382   b = 93.397   c = 106.039 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.205 for 43361 reflections in the resolution range 22.57 to 2.15 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)