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NDB ID: PD0584    PDB ID: 1U8B 


Title:

CRYSTAL STRUCTURE OF THE METHYLATED N-ADA/DNA COMPLEX

Molecular Description:

Ada polyprotein/DNA Complex

Deposited:

2004-08-05

Released:

2005-10-11

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 4 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

He, C., Hus, J.C., Sun, L.J., Zhou, P., Norman, D.P., Dotsch, V., Wei, H., Gross, J.D., Lane, W.S., Wagner, G., Verdine, G.L.
A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada. 
Mol.Cell, 20, pp. 117 - 129, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 28.842   b = 84.593   c = 108.357 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.235 for 21153 reflections in the resolution range 39.4 to 2.1 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)