NDB ID: PD0593    PDB ID: 1XC9 

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Title:

STRUCTURE OF A HIGH-FIDELITY POLYMERASE BOUND TO A BENZO[A]PYRENE ADDUCT THAT BLOCKS REPLICATION

Molecular Description:

DNA polymerase I (E.C.2.7.7.7)/DNA Complex

Deposited:

2004-09-01

Released:

2004-12-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hsu, G.W., Huang, X., Luneva, N.P., Geacintov, N.E., Beese, L.S.
Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication 
J.Biol.Chem., 280, pp. 3764 - 3770, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 88.752   b = 93.733   c = 104.512 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2211 for 67114 reflections in the resolution range 42.76 to 1.9 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1

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