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NDB ID: PD0605    PDB ID: 1XSN 


Title:

CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH A ONE NUCLEOTIDE DNA GAP AND DDTTP

Molecular Description:

Deposited:

2004-10-19

Released:

2005-01-18

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Kunkel, T.A., Pedersen, L.C.
A closed conformation for the Pol lambda catalytic cycle. 
Nat.Struct.Mol.Biol., 12, pp. 97 - 98, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 56.043   b = 62.551   c = 139.83 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.213 for 33027 reflections in the resolution range 35.84 to 1.95 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)