A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 3-Mar-2021 number of released structures: 11234
Search for released structures

NDB ID: PD0606    PDB ID: 1XSP 


Title:

CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH NICKED DNA AND PYROPHOSPHATE

Molecular Description:

5'-D(*CP*GP*GP*CP*CP*GP*TP*AP*CP*TP*G)-3'/ 5'-D(*CP*AP*GP*TP*AP*CP*G)-3'/ 5'-D(P*GP*CP*CP*G)-3'/ DNA polymerase lambda

Deposited:

2004-10-19

Released:

2005-01-18

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Kunkel, T.A., Pedersen, L.C.
A closed conformation for the Pol lambda catalytic cycle. 
Nat.Struct.Mol.Biol., 12, pp. 97 - 98, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 55.845   b = 62.758   c = 140.72 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.206 for 24337 reflections in the resolution range 41.72 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)