A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 18-Nov-2020 number of released structures: 11059
Search for released structures

NDB ID: PD0691    PDB ID: 2A66 


Title:

HUMAN LIVER RECEPTOR HOMOLOGUE DNA-BINDING DOMAIN (HLRH-1 DBD) IN COMPLEX WITH DSDNA FROM THE HCYP7A1 PROMOTER

Molecular Description:

Orphan nuclear receptor NR5A2/DNA Complex

Deposited:

2005-07-01

Released:

2005-12-06

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Solomon, I.H., Hager, J.M., Safi, R., McDonnell, D.P., Redinbo, M.R., Ortlund, E.A.
Crystal Structure of the Human LRH-1 DBD-DNA Complex Reveals Ftz-F1 Domain Positioning is Required for Receptor Activity. 
J.Mol.Biol., 354, pp. 1091 - 1102, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43

Cell Constants:

a = 40.77   b = 40.77   c = 104.85 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.196 for 8437 reflections in the resolution range 22.24 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)