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NDB ID: PD0700    PDB ID: 2ALZ 


Title:

TERNARY COMPLEX OF HPOLI WITH DNA AND DCTP

Molecular Description:

DNA polymerase iota (E.C.2.7.7.7)/DNA Complex

Deposited:

2005-08-08

Released:

2005-10-25

Structural Keywords:

RH DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Nair, D.T., Johnson, R.E., Prakash, L., Prakash, S., Aggarwal, A.K.
Human DNA Polymerase iota Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair. 
Structure, 13, pp. 1569 - 1577, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 98.114   b = 98.114   c = 202.823 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.0 for 20339 reflections in the resolution range 50.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)