A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 22-Sep-2021 number of released structures: 11699
Search for released structures

NDB ID: PD0707    PDB ID: 2AS5 


Title:

STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.

Molecular Description:

Nuclear factor of activated T-cells
cytoplasmic 2/ Forkhead box protein P2/DNA Complex

Deposited:

2005-08-22

Released:

2006-08-08

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Wu, Y., Borde, M., Heissmeyer, V., Feuerer, M., Lapan, A.D., Stroud, J.C., Bates, D.L., Guo, L., Han, A., Ziegler, S.F., Mathis, D., Benoist, C., Chen, L., Rao, A.
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT. 
Cell(Cambridge,Mass.), 126, pp. 375 - 387, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 65.455   b = 157.447   c = 67.666 (Ångstroms)

α = 90.0   β = 118.67   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2382 for 29530 reflections in the resolution range 30.0 to 2.7 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)