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NDB ID: PD0721    PDB ID: 2BCQ 


Title:

DNA POLYMERASE LAMBDA IN COMPLEX WITH A DNA DUPLEX CONTAINING AN UNPAIRED DTMP

Molecular Description:

DNA polymerase lambda (E.C.2.7.7.7
E.C.4.2.99.-)/DNA Complex

Deposited:

2005-10-19

Released:

2006-03-07

Structural Keywords:

B DOUBLE HELIX, BULGES, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Pedersen, L.C., Kunkel, T.A.
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase 
Cell(Cambridge,Mass.), 124, pp. 331 - 342, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 56.044   b = 62.539   c = 139.644 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.206 for 55284 reflections in the resolution range 41.74 to 1.65 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)