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NDB ID: PD0739    PDB ID: 2D5V     NAKB(beta): PD0739 


Title:

CRYSTAL STRUCTURE OF HNF-6ALPHA DNA-BINDING DOMAIN IN COMPLEX WITH THE TTR PROMOTER

Molecular Description:

Hepatocyte nuclear factor 6/DNA Complex

Deposited:

2005-11-07

Released:

2006-12-05

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Iyaguchi, D., Yao, M., Watanabe, N., Nishihira, J., Tanaka, I.
DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6 
Structure, 15, pp. 75 - 83, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 2 1

Cell Constants:

a = 73.02   b = 38.958   c = 106.5 (Ångstroms)

α = 90.0   β = 107.63   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.247 for 34945 reflections in the resolution range 10.0 to 2.0 Ångstroms with Fobs >  3.0 sigma(Fobs) and with I >  0.0 sigma(I)