NDB ID: PD0745    PDB ID: 2F55     NAKB: PD0745 

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Title:

TWO HEPATITIS C VIRUS NS3 HELICASE DOMAINS COMPLEXED WITH THE SAME STRAND OF DNA

Molecular Description:

polyPROTEIN/DNA Complex

Deposited:

2005-11-25

Released:

2005-12-06

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Mackintosh, S.G., Lu, J.Z., Jordan, J.B., Harrison, M.K., Sikora, B., Sharma, S.D., Cameron, C.E., Raney, K.D., Sakon, J.
Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus 
J.Biol.Chem., 281, pp. 3528 - 3535, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 108.2   b = 109.8   c = 183.4 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2467 for 27936 reflections in the resolution range 50.0 to 3.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1 2 

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

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