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NDB ID: PD0754    PDB ID: 2F8X 


Title:

CRYSTAL STRUCTURE OF ACTIVATED NOTCH, CSL AND MAML ON HES-1 PROMOTER DNA SEQUENCE

Molecular Description:

PROTEIN/DNA Complex

Deposited:

2005-12-04

Released:

2006-04-04

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Nam, Y., Sliz, P., Song, L., Aster, J.C., Blacklow, S.C.
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. 
Cell(Cambridge,Mass.), 124, pp. 973 - 983, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 63 2 2

Cell Constants:

a = 273.866   b = 273.866   c = 121.016 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.241 for 72848 reflections in the resolution range 44.82 to 3.25 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)