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NDB ID: PD0837    PDB ID: 2DTU 


Title:

CRYSTAL STRUCTURE OF THE BETA HAIRPIN LOOP DELETION VARIANT OF RB69 GP43 IN COMPLEX WITH DNA CONTAINING AN ABASIC SITE ANALOG

Molecular Description:

DNA polymerase (E.C.2.7.7.7)/DNA Complex

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hogg, M., Aller, P., Konigsberg, W., Wallace, S.S., Doublie, S.
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. 
J.Biol.Chem., 282, pp. 1432 - 1444, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 133.074   b = 123.061   c = 164.564 (Ångstroms)

α = 90.0   β = 96.78   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 376279 reflections in the resolution range 50.0 to 2.37 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)