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NDB ID: PD0841    PDB ID: 2HOT 


Title:

PHAGE SELECTED HOMEODOMAIN BOUND TO MODIFIED DNA

Molecular Description:

Segmentation polarity homeobox protein engrailed/DNA Complex

Deposited:

2006-07-16

Released:

2006-12-12

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Simon, M.D., Feldman, M.E., Rauh, D., Maris, A.E., Wemmer, D.E., Shokat, K.M.
Structure and properties of a re-engineered homeodomain protein-DNA interface. 
Acs Chem.Biol., 1, pp. 755 - 760, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 127.856   b = 45.046   c = 73.568 (Ångstroms)

α = 90.0   β = 118.65   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.22424 for 15927 reflections in the resolution range 34.88 to 2.19 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)