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NDB ID: PD0891    PDB ID: 2NOB     NAKB: PD0891 


Title:

STRUCTURE OF CATALYTICALLY INACTIVE H270A HUMAN 8-OXOGUANINE GLYCOSYLASE CROSSLINKED TO 8-OXOGUANINE DNA

Molecular Description:

Deposited:

2006-10-25

Released:

2006-11-21

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Radom, C.T., Banerjee, A., Verdine, G.L.
Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. 
J.Biol.Chem., 282, pp. 9182 - 9194, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 92.359   b = 92.359   c = 211.726 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 30891 reflections in the resolution range 50.0 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)