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NDB ID: PD0923    PDB ID: 2BQR 


Title:

DNA ADDUCT BYPASS POLYMERIZATION BY SULFOLOBUS SOLFATARICUS DPO4. ANALYSIS AND CRYSTAL STRUCTURES OF MULTIPLE BASE-PAIR SUBSTITUTION AND FRAMESHIFT PRODUCTS WITH THE ADDUCT 1,N2-ETHENOGUANINE

Molecular Description:

DNA POLYMERASE IV (E.C.2.7.7.7)

Deposited:

2005-04-27

Released:

2005-06-23

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zang, H., Goodenough, A.K., Choi, J.Y., Irimia, A., Loukachevitch, L.V., Kozekov, I.D., Angel, K.C., Rizzo, C.J., Egli, M., Guengerich, F.P.
DNA Adduct Bypass Polymerization by Sulfolobus Solfataricus DNA Polymerase Dpo4: Analysis and Crystal Structures of Multiple Base Pair Substitution and Frameshift Products with the Adduct 1,N2-Ethenoguanine. 
J.Biol.Chem., 280, pp. 29750 - , 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 95.528   b = 103.027   c = 53.097 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.223 for 20350 reflections in the resolution range 42.32 to 2.37 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)