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NDB ID: PD0926    PDB ID: 2C22 


Title:

EFFICIENT AND HIGH FIDELITY INCORPORATION OF DCTP OPPOSITE 7,8- DIHYDRO-8-OXODEOXYGUANOSINE BY SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4

Molecular Description:

DNA POLYMERASE IV (E.C.2.7.7.7)

Deposited:

2005-09-26

Released:

2005-11-29

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zang, H., Irimia, A., Choi, J.-Y., Angel, K.C., Loukachevitch, L.V., Egli, M., Guengerich, F.P.
Efficient and High Fidelity Incorporation of Dctp Opposite 7,8-Dihydro-8-Oxodeoxyguanosine by Sulfolobus Solfataricus DNA Polymerase Dpo4 
J.Biol.Chem., 281, pp. 2358 - , 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 93.277   b = 103.91   c = 52.498 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.23 for 17101 reflections in the resolution range 32.47 to 2.56 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)