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NDB ID: PD0948    PDB ID: 2O4I 


Title:

STRUCTURE OF TREX1 IN COMPLEX WITH DNA

Molecular Description:

Three prime repair exonuclease 1 (E.C.3.1.11.2/DNA Complex

Deposited:

2006-12-04

Released:

2007-03-13

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Brucet, M., Querol-Audi, J., Serra, M., Ramirez-Espain, X., Bertlik, K., Ruiz, L., Lloberas, J., Macias, M.J., Fita, I., Celada, A.
Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains. 
J.Biol.Chem., 282, pp. 14547 - 14557, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 80.758   b = 80.758   c = 171.22 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.24516 for 6402 reflections in the resolution range 24.85 to 3.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)