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NDB ID: PD0957    PDB ID: 2O93 


Title:

CRYSTAL STRUCTURE OF NFAT BOUND TO THE HIV-1 LTR TANDEM KAPPAB ENHANCER ELEMENT

Molecular Description:

actor of activated T-cells
cytoplasmic 2/DNA

Deposited:

2006-12-13

Released:

2007-06-19

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bates, D.L., Barthel, K.K., Wu, Y., Kalhor, R., Stroud, J.C., Giffin, M.J., Chen, L.
Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element 
Structure, 16, pp. 684 - 694, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 93.691   b = 95.299   c = 159.227 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.225 for 25518 reflections in the resolution range 30.0 to 3.05 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)