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NDB ID: PD0963    PDB ID: 2O61 


Title:

CRYSTAL STRUCTURE OF NFKB, IRF7, IRF3 BOUND TO THE INTERFERON-B ENHANCER

Molecular Description:

Transcription factor p65/Interferon regulatory factor 7/Interferon regulatory factor 3 fusion protein
Nuclear factor NF-kappa-B p105 subunit/DNA Complex

Deposited:

2006-12-06

Released:

2007-07-24

Structural Keywords:

B DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Panne, D., Maniatis, T., Harrison, S.C.
An Atomic Model of the Interferon-beta Enhanceosome. 
Cell(Cambridge,Mass.), 129, pp. 1111 - 1123, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 95.222   b = 116.37   c = 134.237 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 37592 reflections in the resolution range 40.65 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)