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NDB ID: PD1009    PDB ID: 2PI0 


Title:

CRYSTAL STRUCTURE OF IRF-3 BOUND TO THE PRDIII-I REGULATORY ELEMENT OF THE HUMAN INTERFERON-B ENHANCER

Molecular Description:

Interferon regulatory factor 3/DNA Complex

Deposited:

2007-04-12

Released:

2007-10-30

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Escalante, C.R., Nistal-Villan, E., Shen, L., Garcia-Sastre, A., Aggarwal, A.K.
Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. 
Mol.Cell, 26, pp. 703 - 716, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 173.417   b = 46.132   c = 129.325 (Ångstroms)

α = 90.0   β = 129.42   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.18519 for 28772 reflections in the resolution range 50.0 to 2.31 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)