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NDB ID: PD1040    PDB ID: 2R8H 


Title:

SELECTIVITY OF NUCLEOSIDE TRIPHOSPHATE INCORPORATION OPPOSITE 1,N2-PROPANODEOXYGUANOSINE (PDG) BY THE SULFOLOBUS SOLFATARICUS DNA POLYMERASE DPO4 POLYMERASE

Molecular Description:

DNA polymerase IV (E.C.2.7.7.7)/DNA

Deposited:

2007-09-10

Released:

2008-07-22

Structural Keywords:

B DOUBLE HELIX, OPEN HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, Y., Musser, S.K., Saleh, S., Marnett, L.J., Egli, M., Stone, M.P.
Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV 
Biochemistry, 47, pp. 7322 - 7334, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 93.4   b = 103.0   c = 52.8 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2151 for 15421 reflections in the resolution range 50.0 to 2.48 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)