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NDB ID: PD1046    PDB ID: 3B6F 


Title:

NUCLEOSOME CORE PARTICLE TREATED WITH CISPLATIN

Molecular Description:

Histone H3.2
Histone H4
Histone H2A
Histone H2B 1.1/DNA Complex

Deposited:

2007-10-29

Released:

2007-12-25

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Wu, B., Droge, P., Davey, C.A.
Site selectivity of platinum anticancer therapeutics 
Nat.Chem.Biol., 4, pp. 110 - 112, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 106.327   b = 109.38   c = 180.585 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.331 for 28106 reflections in the resolution range 93.66 to 3.45 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)