NDB ID: PD1220    PDB ID: 3FSI 

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Title:

CRYSTAL STRUCTURE OF A TRYPANOCIDAL 4,4'-BIS(IMIDAZOLINYLAMINO)DIPHENYLAMINE BOUND TO DNA

Molecular Description:

Reverse transcriptase domain (E.C.2.7.7.49)

Deposited:

2009-01-09

Released:

2009-05-19

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Glass, L.S., Nguyen, B., Goodwin, K.D., Dardonville, C., Wilson, W.D., Long, E.C., Georgiadis, M.M.
Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA. 
Biochemistry, 48, pp. 5943 - 5952, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 53.743   b = 145.592   c = 46.57 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 34619 reflections in the resolution range 50.0 to 1.75 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

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