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NDB ID: PD1235    PDB ID: 3G6U 


Title:

GR DNA-BINDING DOMAIN:FKBP5 16BP COMPLEX-49

Molecular Description:

Glucocorticoid receptor/DNA Complex

Deposited:

2009-02-08

Released:

2009-04-21

Structural Keywords:

B DOUBLE HELIX, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Meijsing, S.H., Pufall, M.A., So, A.Y., Bates, D.L., Chen, L., Yamamoto, K.R.
DNA binding site sequence directs glucocorticoid receptor structure and activity. 
Science, 324, pp. 407 - 410, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 116.243   b = 39.088   c = 95.61 (Ångstroms)

α = 90.0   β = 122.67   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.191 for 25112 reflections in the resolution range 34.375 to 1.9 Ångstroms with Fobs >  0.12 sigma(Fobs) and with I >  0.0 sigma(I)