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NDB ID: PD1252    PDB ID: 3GII 


Title:

DPO4 EXTENSION TERNARY COMPLEX WITH DISORDERED A OPPOSITE AN OXOG IN ANTI CONFORMATION

Molecular Description:

DNA polymerase IV (E.C.2.7.7.7)

Deposited:

2009-03-05

Released:

2009-05-19

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rechkoblit, O., Malinina, L., Cheng, Y., Geacintov, N.E., Broyde, S., Patel, D.J.
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. 
Structure, 17, pp. 725 - 736, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 95.761   b = 111.646   c = 52.708 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.205 for 16924 reflections in the resolution range 20.0 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)