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NDB ID: PD1270    PDB ID: 3GP1 


Title:

MUTM ENCOUNTERING AN INTRAHELICAL 8-OXOGUANINE (OXOG) LESION IN EC3-V222P COMPLEX

Molecular Description:

DNA glycosylase (E.C.4.2.99.18)

Deposited:

2009-03-20

Released:

2009-11-10

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Qi, Y., Spong, M.C., Nam, K., Banerjee, A., Jiralerspong, S., Karplus, M., Verdine, G.L.
Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme 
Nature, 462, pp. 762 - 766, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 45.613   b = 92.845   c = 105.019 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.189 for 27498 reflections in the resolution range 45.69 to 2.05 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)