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NDB ID: PD1282    PDB ID: 3GV8 


Title:

HUMAN DNA POLYMERASE IOTA IN COMPLEX WITH T TEMPLATE DNA AND INCOMING DGTP

Molecular Description:

DNA polymerase iota/DNA

Deposited:

2009-03-30

Released:

2009-06-02

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kirouac, K.N., Ling, H.
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota 
Embo J., 28, pp. 1644 - 1654, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 98.07   b = 98.07   c = 203.38 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.219 for 39636 reflections in the resolution range 23.84 to 2.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)