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NDB ID: PDE0136    PDB ID: 1KSP 


Title:

DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX

Molecular Description:

DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX

Deposited:

1997-08-19

Released:

1998-02-25

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Brautigam, C.A., Steitz, T.A.
Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. 
J.Mol.Biol., 277, pp. 363 - 377, 1998.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43

Cell Constants:

a = 101.56   b = 101.56   c = 85.25 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.0 for 31495 reflections in the resolution range 20.0 to 2.3 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)