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NDB ID: PDE083    PDB ID: 8ICV 


Title:

DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR)

Molecular Description:

DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYGUANOSINE-5'- TRIPHOSPHATE
SOAKED IN THE PRESENCE OF DGTP AND MNCL2

Deposited:

1996-01-04

Released:

1996-11-15

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Pelletier, H., Sawaya, M.R., Wolfle, W., Wilson, S.H., Kraut, J.
A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta 
Biochemistry, 35, pp. 12762 - 12777, 1996.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 179.019   b = 57.629   c = 48.283 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the TNT program. The R value is 0.159 for 7948 reflections in the resolution range 20.0 to 3.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)