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NDB ID: PDT015    PDB ID: 1NFK 


Title:

STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER

Molecular Description:

NUCLEAR FACTOR KAPPA-B (NF-KB)/DNA COMPLEX

Deposited:

1995-02-28

Released:

1996-12-23

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASE

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ghosh, G., van Duyne, G., Ghosh, S., Sigler, P.B.
Structure of NF-kappa B p50 homodimer bound to a kappa B site. 
Nature, 373, pp. 303 - 310, 1995.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 84.2   b = 132.1   c = 80.1 (Ångstroms)

α = 90.0   β = 93.1   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.23 for 28020 reflections in the resolution range 6.0 to 2.3 Ångstroms with Fobs >  3.0 sigma(Fobs) and with I >  0.0 sigma(I)