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NDB ID: PH0001    PDB ID: 1QBJ 


Title:

CRYSTAL STRUCTURE OF THE ZALPHA Z-DNA COMPLEX

Molecular Description:

DOUBLE-STRANDED RNA SPECIFIC ADENOSINE DEAMINASE (ADAR1)/DNA COMPLEX

Deposited:

1999-04-22

Released:

1999-07-02

Structural Keywords:

Z DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Schwartz, T., Rould, M.A., Lowenhaupt, K., Herbert, A., Rich, A.
Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA. 
Science, 284, pp. 1841 - 1845, 1999.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 4 21 2

Cell Constants:

a = 85.9   b = 85.9   c = 71.3 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.227 for 13519 reflections in the resolution range 6.0 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)