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NDB ID: PH0039    PDB ID: 2PPB 


Title:

CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNAP POLYMERASE ELONGATION COMPLEX WITH THE NTP SUBSTRATE ANALOG AND ANTIBIOTIC STREPTOLYDIGIN

Molecular Description:

DNA-directed RNA polymerase/DNA/RNA/Streptolydigin Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Vassylyev, D.G., Vassylyeva, M.N., Zhang, J., Palangat, M., Artsimovitch, I., Landick, R.
Structural basis for substrate loading in bacterial RNA polymerase. 
Nature, 448, pp. 163 - 168, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41

Cell Constants:

a = 155.379   b = 155.379   c = 496.992 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.234 for 207148 reflections in the resolution range 40.0 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)