A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 25-May-2016 number of released structures: 8217
Search for released structures

NDB ID: PH0045    PDB ID: 3BSU 


Title:

HYBRID-BINDING DOMAIN OF HUMAN RNASE H1 IN COMPLEX WITH 12-MER RNA/DNA

Molecular Description:

Ribonuclease H1 (E.C.3.1.26.4)/RNA/DNA

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Nowotny, M., Cerritelli, S.M., Ghirlando, R., Gaidamakov, S.A., Crouch, R.J., Yang, W.
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD. 
Embo J., 27, pp. 1172 - 1181, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 45.492   b = 64.262   c = 140.322 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.0 for 23892 reflections in the resolution range 50.0 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)