CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN
RNA-BINDING PROTEIN NOVA-2/RNA
SINGLE STRAND, LOOP, FLIPPED-OUT BASES
Chain C, D
Chain A, B
Lewis, H.A., Musunuru, K., Jensen, K.B., Edo, C., Chen, H., Darnell, R.B., Burley, S.K.
Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
Cell(Cambridge,Mass.), 100, pp. 323 - 332, 2000.
P 21 21 21
a = 47.85 b = 51.21 c = 128.6 (Ångstroms)
α = 90.0 β = 90.0 γ = 90.0 (degrees)
The structure was refined using the CNS program. The R value is 0.215 for 12459 reflections in the resolution range 20.0 to 2.4 Ångstroms with Fobs > 0.0 sigma(Fobs) and with I > 3.0 sigma(I)