A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 20-Jul-2016 number of released structures: 8375
Search for released structures

NDB ID: PR0074    PDB ID: 1M5K 


Title:

CRYSTAL STRUCTURE OF A HAIRPIN RIBOZYME IN THE CATALYTICALLY-ACTIVE CONFORMATION

Molecular Description:

U1 SMALL NUCLEAR RIBONUCLEOPROTEIN/RNA INHIBITOR/RNA RIBOZYME COMPLEX

Structural Keywords:

DOUBLE HELIX, LOOP, BULGES, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rupert, P.B., Massey, A.P., Sigurdsson, S.T., Ferre-D'Amare, A.R.
Transition state stabilization by a catalytic RNA 
Science, 298, pp. 1421 - 1424, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 256.3   b = 44.1   c = 102.4 (Ångstroms)

α = 90.0   β = 109.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.23 for 41156 reflections in the resolution range 61.07 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)