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NDB ID: PR0077    PDB ID: 1M5V 


Title:

TRANSITION STATE STABILIZATION BY A CATALYTIC RNA

Molecular Description:

U1 SMALL NUCLEAR RIBONUCLEOPROTEIN/RNA INHIBITOR/RNA RIBOZYME COMPLEX

Structural Keywords:

DOUBLE HELIX, LOOP, BULGES, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rupert, P.B., Massey, A.P., Sigurdsson, S.T., Ferre-D'Amare, A.R.
Transition state stabilization by a catalytic RNA 
Science, 298, pp. 1421 - 1424, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 258.648   b = 44.258   c = 102.174 (Ångstroms)

α = 90.0   β = 107.69   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.221 for 43428 reflections in the resolution range 19.7 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)